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In the absence of extrinsic neural or hormonal influences, the SA node would discharge at a rate of about 100 impulses per minute.

Heart rate and cardiac output, however, must vary in response to the needs of the body’s cells for oxygen and nutrients.

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Autonomic nervous system control of the cardiovascular system originates in the medulla oblongata of the brain.

Two specialized neural pathways-the parasympathetic and the sympathetic nervous systems-have direct influences on the heart.

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