Current international guidelines need to be revised in the light of the recent evidence.Research into aspects of pharmacokinetics and efficacy and adverse effect profiles of bilastine in children under 12 years of age is needed as are dose-response assessments and studies planned rigorously with the aim of assessing quality of life effects.These are unfortunate myths as children are fully able to display the appropriate response to pain.
In the first trial, bilastine reduced the mean AUC of TSS to a similar extent as cetirizine and to a significantly greater extent than placebo (p A third phase III, double-blind study compared the efficacy of bilastine 20mg, levocetirizine 5mg and placebo once daily for 28 days in patients with moderate to severe chronic idiopathic urticaria (n=525).
Marcus Maurer, Department of Dermatology and Allergy, Allergie-Centrum-Charité, Charité – Universitätsmedizin Berlin, Charitéplatz 1, DE-10117 Berlin, Germany.
E-mail: [email protected] spontaneous urticaria (CSU) is one of the most frequent skin disorders.
These actions are taken so that the procedure can be performed more smoothly.
CLINICAL STUDIESIn two phase III, double-blind studies (n=683, n=721), bilastine 20mg was compared with cetirizine 10mg or desloratadine 5mg and placebo once daily for the treatment of seasonal allergic rhinitis.