Many of the brand names above are for these combination medicines.
These are meant to treat many symptoms at the same time.
Some drugs contain diphenhydramine alone (such as Nytol, Sleep-Eez, and Sominex), while others contain combinations of diphenhydramine with pain relievers (such as Anacin P. Unfortunately, most of these drugs leave patients feeling drowsy the next day and may not be very effective in providing restful sleep.Some people deliberately choose to abuse antihistamines, often as a substitute when they can't get their drug of choice.Others may start out using an antihistamine as a sleep aid but find they need higher and higher doses to fall asleep. They are available in pills or liquids, nasal sprays or gels, and eyedrops. This can cause itching, sneezing, runny nose, and watery eyes.Two types of OTC antihistamines are available: first-generation and second-generation. First-generation antihistamines are sometimes used in OTC . Antihistamines prevent histamines from attaching to your cells and causing symptoms.